Lost in the Maze? Navigating Evidence and Ethics in Translational Neuroscience

Beginn: Uhr
Ende: Uhr
Schloss Herrenhausen
Fachpublikum Wissenschaft

The Herrenhausen Conference on February 14-16, 2018 in Hannover focuses on new treatment modalities of novel neurological interventions in the light of the ethical challenges concerning the personal despair.

Confronted with a neurodegenerative disease: How will life go on being a newly diagnosed individual? (Foto: jozefmicic – fotolia.com)

This Herrenhausen Conference focuses on major scientific and ethical challenges of novel neurological interventions and how they can be overcome. Participants will explore how critically needed trials of new treatment modalities can be launched safely and conducted ethically.
Since most major neurological disorders like Alzheimer's, traumatic brain injuries, Amyothrophic Lateral Sclerosis, and many others have no cure, the despair of patients means they often fail to consider the major risks intrinsic to early clinical trials of novel modalities such as stem cell interventions and gene therapy. While these new pathways to potential treatments need to be pursued, they are being developed in a climate that often is not conducive to good science. Factors such as concerns about irreproducible research results, researchers' needs to divide their time between their research and pursuing funding, and the inflated expectations produced by science hype can all hinder efforts to conduct investigations carefully and responsibly. To help improve this problematic climate, the Herrenhausen Conference will address:

1. The personal despair and public hype that frame contemporary scientific research in neurological disease.
2. Deficiencies in pre-clinical neurological research and how to overcome them in order to increase the safety and predictive value of early trials of novel neurological interventions.
3. Strategies that can improve the informed consent processes for trials of these novel interventions.

The conference will seek clear deliverables to improve the robustness and positive predictive value of pre-clinical research, protect the welfare of research participants, and develop more effective informed consent processes.

We invite all researchers and experts working in this field. There is no fee for the attendance, but registration is essential.

Herrenhausen Conference
"Lost in the Maze? Navigating Evidence and Ethics in Translational Neuroscience"
February 14 - 16, 2018
Herrenhausen Palace, Hanover, Germany


Mark Yarborough, University of California Davis, USA
Ulrich Dirnagl, Charité Berlin and Berlin Institute of Health, Germany

Organizing Committee 

Annelien Bredenoord, Utrecht University, The Netherlands
Ulrich Dirnagl, Charité Berlin and Berlin Institute of Health, Germany
Nanette Joyce, University of California Davis, USA
Jonathan Kimmelman, McGill University, Canada
Ubaka Ogbogu, University of Alberta, Canada
Emily Sena, University of Edinburgh, UK
Daniel Strech, Hannover Medical School, Germany
Mark Yarborough, University of California Davis, USA
Flavio D'Abramo, Charité Berlin and Freie Universität Berlin


Please find the etailed program in the column on the right.

Confirmed Speakers and Session Chairs

Alison Abbott (Nature Publishing Group/USA), Enrica Alteri (European Medicines Agency/UK), Christopher Baum (Hannover Medical School/Germany), Julie Belluz (Vox.com/USA), Annelien Bredenoord (Utrecht University/The Netherlands), Virginie Bros-Facer (Eurordis/France), Dominique Brossard (University of Wisconsin-Madison/USA), Leena Bruckner-Tuderman (Albert-Ludwigs-University of Freiburg and Deutsche Forschungsgemeinschaft/Germany), Alex Capron (University of Southern California/USA), Timothy Caulfield (University of Alberta/Canada), Iain Chalmers (James Lind Initiative/UK), Katherine Cowan (James Lind Alliance/UK), Ulrich Dirnagl (Charité Berlin and Berlin Institute of Health/Germany), Cornelius Frömmel (Charité Berlin/Germany), Jodi Halpern (University of California Berkeley /USA), Insoo Hyun (Case Western Reserve University/USA), John Ioannidis (Stanford University/USA), Sharon McClellan Thomason (Help 4 HD International), Nanette Joyce (University of California Davis/USA),  Scott Kim (National Institutes of Health/USA), Jonathan Kimmelman (McGill University/Canada), Paul Knoepfler (University of California Davis/USA), Alex Kolodkin (Johns Hopkins School of Medicine/USA), Wilhelm Krull (Volkswagen Foundation/Germany), Andreas Meisel (Charité Berlin/Germany), Andreas Meyer-Lindenberg (Central Institute of Mental Health/Germany), Frank Miedema (University Medical Center Utrecht/The Netherlands), Jeffrey Mogil (McGill University/Canada), Ubaka Ogbogu (University of Alberta/Canada), Sarah Perrault (University of California Davis/USA), Laurent Pradier (Sanofi/France), Bernard Ravina (Voyager Therapeutics/USA), Michael Rieder (Concerned parent, Germany), Emily Sena (University of Edinburgh/UK), Shai Silberberg (National Institutes of Health/USA), Daniel Strech (Hannover Medical School/Germany), Thomas Steckler (Janssen Pharmaceutics/Belgium), Hanno Würbel (University of Bern/Switzerland), Mark Yarborough (University of California Davis/USA) 


There are no fees for attendance but registration is essential. If you would like to attend the conference, please register by clicking on the registration link in the column on the right.


The conference language is English.

Credit Points for German Physicians

Approved as "Fortbildungsveranstaltung gemäß der Fortbildungsordnung der Ärztekammer Niedersachsen" Veranstaltungsnummer: 2760302018003500000, www.aekn.de.

Venue and Public Transport

The conference is held at Herrenhausen Palace, a modern conference center in Hanover, Germany. You can reach the venue by tram: Take line 4 or 5 and get off at "Herrenhäuser Gärten".

Accommodation for Participants

Please note that you are responsible for booking your accommodation. As Hannover is a city that hosts many fairs, we recommend booking a hotel as soon as you register.


Please cancel your registration if you cannot attend the conference. We have a waiting list for the meeting and can offer your place to another person if you cannot attend. Simply use the registration tool to cancel or send us an email.

Herrenhausen Conferences

With its Herrenhausen Conferences the Volkswagen Foundation provides international experts as well as junior researchers with a platform for an intense interdisciplinary dialogue on exciting new areas of research and innovative methodological approaches. The main focus of the conferences does lie on the current challenges faced by each research area rather than on further in-depth discussions and analyses of individual well-established topics. We are interested in unanswered questions and unsolved problems - and in the respective research field's relevance for society.